Are spinal cord injuries permanent?
While physical damage to the spinal cord is permanent, some functions affected by spinal cord injury can be recovered through neuroplasticity (the central nervous system’s ability to rewire itself).
This article will go over the permanent effects of spinal cord injury and explain why there is hope for healing.
Let’s get started!
Are Spinal Cord Injuries Permanent?
Physical damage to the spinal cord is permanent because it is very difficult for neurons in the central nervous system to regenerate.
Axonal regeneration in the spinal cord is possible; however, there are many barriers that prevent it from happening.
After a spinal cord injury, the spinal cord is left in a very hectic state consisting of:
- Cell deaths
- Limited/ loss of blood supply
- Excitotoxicity (damage to neurons caused by hyperactive neurotransmitters)
All these factors contribute to tissue loss and the formation of cysts and glial scarring at the site of injury.
Glial scarring blocks axonal regeneration across the site of injury and restricts recovery potential.
Hope for Spinal Cord Injury Recovery
Spinal cord injury recovery can be divided into 2 parts: neuroprotection and neuroregeneration.
Neuroprotection is all about limiting damage to the spinal cord.
While the damage caused by the initial impact of the spinal cord injury cannot be controlled, seeking immediate medical attention will help stabilize the spinal cord and minimize damage caused by secondary processes like swelling, inflammation, and excitotoxicity.
Neuroprotection is time-sensitive and must be carried out within the acute phase (the first 48 hours) of injury.
Neuroregeneration focuses on promoting neuroplasticity in the spinal cord so that functions can be recovered.
Because transected or compressed neurons have very little recovery potential, SCI recovery relies heavily on the adaptive properties of neurons spared by the injury.
Spared neural pathways can utilize neuroplasticity to reorganize their circuits and sprout new axons.
Neuroplasticity is powered by your actions. The more repetitions you perform, the more rewiring occurs and the stronger neural pathways for that action become.
However, neuroplasticity is limited, so the severity of your spinal cord injury will affect chances of recovery.
How Severity of Injury Affects Recovery Outlook
The ability to heal after spinal cord injury primarily depends on the completeness of your injury.
Spinal cord injuries can be complete or incomplete.
A complete spinal cord injury occurs when the spinal cord is severed all the way through, leaving no intact neural connections running through the brain and areas below your level of injury.
In contrast, an incomplete spinal cord injury is when only part of the spinal cord at that level of injury is damaged.
A complete SCI will leave no spared neural pathways while an incomplete SCI can have few or many spared neural pathways.
The more spared neural pathways there are, the greater the recovery potential.
Hope for Individuals with Permanent Paralysis After Spinal Cord Injury
If you have a complete spinal cord injury, or very severe incomplete spinal cord injury, there is still hope to walk again!
Researchers are developing treatments like stem cell therapy and epidural electrical stimulation to promote functional recovery even after complete SCI.
Additionally, robotic exoskeletons are making it possible for paralyzed spinal cord injury patients to maximize their mobility.
Stem Cell Therapy
Stem cells are extremely versatile because they’re able to specialize into a variety of different cell types depending on the environment they’re placed in.
They can also divide infinitely, which makes them ideal for restoring cell count and neural connections after spinal cord injury.
However, there are a few obstacles to stem cell therapy for SCI recovery that need to be worked out like:
- getting through/ limiting the formation of glial scarring
- determining what type of stem cell to use
- optimizing dosages and timing
Epidural Electrical Stimulation
Epidural electrical stimulation involves getting an implant that sends electrical currents to areas below your level of injury.
It works around the spinal cord lesion and uses electrical currents that mimic brain signals to stimulate movement.
However, in addition to using epidural stimulation, spinal cord injury patients need to relearn how to control their movements with intensive physical training.
This study found that by combining intensive physical training and epidural stimulation, even individuals with motor complete injuries were able to improve their motor functions.
Like stem cell therapy, epidural stimulation is still being developed, but the research for it is yielding very promising results.
A robotic exoskeleton can help individuals with completely transected spinal cord injuries walk again.
It’s a wearable device that does the walking, sitting, and standing for you.
Robotic exoskeletons are ideal for individuals with complete spinal cord injuries who may otherwise not be able to walk at all.
Models will vary, but essentially, all you have to do is facilitate the movement by shifting your weight and the exoskeleton will do the rest.
They’re costly ($40,000+) but may be worth the investment if it means you can walk again.
Perspective Determines Whether Your Spinal Cord Injury is Permanent or Not
If you have an incomplete spinal cord injury, there’s no way to know for sure which functions will return.
The body works in miraculous, spontaneous ways, and its ability to adapt after traumatic events like spinal cord injury is unpredictable.
All we know for certain is that the spinal cord has neuroplasticity, which relies heavily on repetition. The more you practice, the stronger neural pathways become.
Physical damage to the spinal cord is permanent. However, depending on the severity of your SCI and how aggressively you pursue rehabilitation, functional recovery may be possible.
It will require a lot of hard work, but as long as you continue to exercise weak movements, you’ll be stimulating and strengthening those neural connections.
Featured image: ©iStock.com/demaerre